Wednesday, July 6, 2011

Safari Time!

Despite our internet being stubborn all week, Shalina and I just submitted the next huge chunk of our project and now we're off for our safari! We're heading to Kampala tonight, and then we'll be safari-ing Thursday-Saturday, coming back to Kiboga Sunday afternoon.

Also we found coffees last weekend!!!

As well as Annie, Laila, and Jessica (classmates of mine from UW doing a whirlwind 4-week project here) who we had a blast hanging out with last Saturday. Hopefully we'll see them this weekend before we leave Kampala again! Also hopefully we will eat lots more coffees :)

Malaria in Pregnancy--A Case Study

I promised I'd post more about my project on malaria in pregnancy, so here is a case study I did of one women who came to Kiboga Hospital with malaria. Even if a woman has grown up in a malaria endemic region like Uganda, when she becomes pregnant the malarial parasites can hide in the placenta and cause severe disease. Severe anemia is the most common complication, which can lead to peripartum and postpartum hemorrhage, and malaria-induced anemia causes the most maternal deaths at Kiboga Hospital. Additionally the parasites in the placenta lead to miscarriages, still births, premature births, and low birth weights, and these infants that are born are at a much increased risk for contracting other diseases and dying in their first few years of life. Here is Juliet's story:
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When I first met Juliet during Monday morning rounds on the maternity ward she seemed like many other women in a similar condition: glad that she no longer felt ill, and very eager to leave the hospital. I learned that Juliet was 24 years old and six months pregnant with her third child, and had been admitted with severe malaria over the weekend. She had recovered well after several doses of IV quinine and was hoping to be discharged that day. I asked the doctor to ask her the questions I’ve been using to survey all pregnant women admitted with malaria, and among other things we learned that she doesn’t sleep under a bed net, did not have malaria in her previous pregnancies or as a child, and had recently emigrated from Rwanda. Her case piqued my interest.

Since Juliet was told she need to wait for another blood smear before she could be discharged I asked the doctor to introduce me and my project and ask if I could come back and chat with her while she waited. She looked surprised and embarrassed as he translated, but shyly looked at me through her long lashes and agreed to the interview. When I found her later (with a nurse who could translate her tricky Rwandan dialect) I noticed that while she still seemed shy she had retied her hair into a beautiful scarf and had changed into a nicer dress; it seemed she was looking forward to the interview as well. Juliet was very quiet and succinct with the male doctor earlier, but once the nurse and I started talking with her she talked very animatedly and used her hands to mime out what she was describing so I could follow along.

I soon learned that Juliet was born and raised in Rwanda. She grew up in a village with her family where they raised cattle and relied on subsistence farming for food. She attended school for five years before school fees became too expensive for her family, so she dropped out and helped her family with “digging” instead. When Juliet was 18 years old she married a cattle farmer, and now she has two daughters ages six and three.

A few months ago a newly pregnant Juliet moved with her husband and her younger daughter to Kiboga District in Uganda to be near her husband’s family, who are cattle farmers in the town of Kiboga. Their oldest daughter is still in Rwanda; she is staying with Juliet’s mother and attending a new, free school mzungus have started in her old village. Juliet’s family is renting a room in a house shared with two other families that is located on the highway about 4 miles outside of Kiboga. Their family is quite poor, and while they eat three meals a day they cannot afford much else.

When Juliet was two months pregnant she fell ill quite suddenly. Juliet said she was shivering uncontrollably, her abdomen felt extremely hot on the inside, she was dizzy, and she had a horrible headache. She was scared and didn’t know what was wrong with her but when she went to Kiboga Hospital for treatment she learned that she had malaria. She had heard of malaria in Rwanda, and knew that people in her village had gotten it before, but neither she nor anyone in her family had ever had it. After getting several doses of IV medication she was discharged with oral medications to take, but since they made her nauseous and caused vomiting she stopped after taking only a few.

This past weekend Juliet, who is now six months pregnant, was digging in her family’s rented land when she started shivering and developed severe joint pain. She decided to stop digging and instead squatted down to begin collecting nuts, but she quickly lost all her energy and returned to the house. She was still shivering and achy and suspected she had malaria again, and so walked the four miles to the hospital for treatment.

I asked Juliet if she knew what malaria is, or what causes it. She is still unsure of what the disease entails since she has had different experiences with it, and had no guesses as to what could cause it. The nurse asked her if she had ever heard of a fever disease caused by mosquitoes, and while Juliet said she hadn’t her face lit up and she explained that she’d had lots of mosquito bites since moving to Kiboga, and asked if they were related to her sicknesses. She used to sleep under a mosquito net in Rwanda but her family cannot afford to buy them here, so she’s been bitten many times at night. She has been attending antenatal classes at the hospital, but doesn’t think they’ve ever mentioned malaria (although she has trouble understanding rapid Lugandan) and she was not given a free bed net. She knows she has been given lots of pills to swallow at antenatal, and thinks she may have received 3 pills to prevent malaria, but she was very unsure.

At the end of our chat I took time to talk with Juliet about malaria and what causes it and explain that her whole family is at risk because they’ve never been exposed to it before. I also explained that malaria can be harmful to her pregnancy, and told her to specifically ask for a bed net at her next antenatal appointment. Finally the nurse and I tried to convince her to complete her oral quinine treatment this time, and made sure she was prescribed an anti-nausea medication to take with it at home.

Juliet thanked us for helping her and her family, and I thanked her for sharing her story with me. As I walked out of the ward I looked back towards her bed to find her still watching me. She broke out in a huge grin—the first one I’d seen from her all day—and waved goodbye to me with both her arms. I waved enthusiastically back and felt lighthearted knowing we had both helped each other that day.

Sunday, July 3, 2011

Week 2: Cases of the Week

Still playing catch up… Posts about Week 3 Cases and this weekend will hopefully happen before we leave town to go !!!SAFARI-ING!!! Wednesday afternoon. FYI this is a clinical post, so it's long and somewhat graphic, so be warned. I'm not offended if you skip this post and wait for more pics of kids and animals! Here's a zebra to tide you over. 



***First Ugandan Theater Experience: Every time Dr. K says “Shall we go to the theater?” I have to pause for a second to remember that he wants to go to the operating theater, not to see a Broadway show. Though we’ve seen quite a few operations now, my first back-to-back C-sections (or “Caesars” as they’re generally called here) will always be memorable.

As you may remember the hospital usually doesn’t have electricity or running water, and the same can be said of the operating theater. There are large tanks of sterilized water located throughout (they look like the Gatorade jugs you see on the side of football fields) for scrubbing in and other uses, and if you’re in the theater after dark—and do enough politicking for hours beforehand—there is sometimes a generator available to run lights and the oxygen machine for the anesthesiologist (BTW we’ve now done two surgeries completely without power, and one where it crapped out for 20 minutes in the middle). We wear the usual caps, masks, and scrubs—the hugest and holey-ist scrubs you can imagine—but also giant, white galoshes, the mandatory OR footwear. We’ll bring the camera to work soon so we can document the ridiculousness of our theater attire.

Our first Caesar was on a woman who had been in labor for 2-3 days by the time she arrived from her village, and though the baby was in the correct position the labor was obstructed. We got into our galoshes and into the OR and had no idea what to expect—neither Shalina nor I had seen a C-section before.

Dr. K made a few quick incisions to get down into things, and with the first touch of the scalpel to the uterus a giant spray of brown liquid erupted out, spraying several feet off the table and quickly sloshing all over the floor. We suddenly understood (and were thankful for) the galoshes. We were understandably distracted for a few seconds by the brown volcano coming from our patient’s abdomen, but Dr. K calmly fished around inside the patient and before I could register the appearance of two baby feet he pulled and twisted and tugged the baby completely free of the mother and had her dangling upside-down by her feet in the air. A nurse came and collected the baby and worked on her while Dr. K and another nurse worked on cleaning up and repairing the mom. All of this happened in the first 3 minutes of the surgery, and I think Shalina and I stared slack-jawed and rooted to the floor the entire time.

When things calmed down we learned the volcano was the result of the long obstructed labor. The placenta had already separated (Dr. K had tossed it out right before he grabbed the baby) and the baby had already had its first bowel movement, which is what tinted the color and caused the gas. The baby was not okay initially but resuscitated well, and although the mom developed sepsis a few days after the surgery both she and her baby are doing well now.

The second Ceaser seemed less dramatic, but it was nice to see a more typical case. This mom had also been in labor for over two days, and CPD (Cephalic-Pelvic Disproportion, or inadequate pelvis size) necessitated operative intervention. With very young and very skinny moms here this is a common cause for a trip to the theater (obstructed labor is the other big ticket item). The operation went smoothly and both mom and baby did well afterwards. We’ve had several less positive Caesar experiences this week, so it was a treat to have our first day in the theater result in two babies.

***The Morgue (WARNING: graphic): This week we learned that if anyone asks you if you want to see a postmortem on anyone in rural Africa, you say no thank you. Before we could start rounds Monday morning three detectives arrived from the police station to request a postmortem exam on a 6 year old girl who had died the day before. The parents said the girl died of malaria, but the neighbors suggested that the girl was beaten to death, so the police were investigating. We learned that beating children is common, culturally acceptable, and legal in Uganda—unless the child dies.

Shalina had never seen a postmortem or an autopsy before and was visibly nervous as we descended into the basement. Although I took the autopsy elective winter quarter, and was putting up a tough front as usual, I was still unsure about seeing a child abuse case. As it got darker and smellier I re-remembered that there’s no electricity at Kiboga (so no lights and no refrigeration), and started to think that this trip to the basement may be a mistake.

We were the last two to go through the double doors into the morgue and froze upon entering. There was a dead man lying on a table right inside the door, only partially covered by a sheet, and although it smelled (reeked) like he had been dead for quite a while his blood was running off the table and into a large, thick puddle on the floor. It was horrifying. Absolutely horrifying. The heat, the smell, and the scene in front of us compelled us to move quickly on, and we followed Dr. K and the detectives into the next room.

The little girl had been carefully wrapped in sheets and was still wearing her Sunday go-to-church dress before she was prepared for the exam. Dr. K was quick and thorough in his external examination while the detectives took photos. It couldn’t have been more than 5-10 minutes, but the smell coming from the next room made it feel at least 10 times as long. Shalina was on the verge of passing out—shaking, nauseous, sweating—waiting for the external exam to turn into an internal one. She was sure she would collapse if Dr. K picked up a scalpel, and so after a few minutes she fled for the sunny outdoors and fresh air (smart girl). Two detectives soon followed. For some reason I forced myself to stick it out (though I was also pretty sure I would lose it in the heat and the smell—the smell!—if Dr. K was going to open her up). When Dr. K explained that the exam was inconclusive and that if the detectives wanted a full autopsy they would have go to Mulago I almost fainted from relief. For some crazy reason I stayed while he filled out the paperwork before returning upstairs, and when we crossed through the outer room with the dead man I didn’t breathe and didn’t look anywhere except the exit.

We went about the rest of our day and tried to shake off the horrifying experience, but the smells wafting up the staircase turned our stomachs and reminded us all day of the man in the basement. Above ground people ate lunch, babies were born, and chickens roamed the halls.

***Mycetoma foot: We didn’t see this case in the hospital, but randomly came across a man begging on the streets of Kampala with a pretty advanced, gnarly mycetoma foot. Thanks to microbiology last quarter this case was too exciting not to add to the end of the list! Mycetomas can have a bacterial or fungal origin, and end up causing the tree stump-looking feet you may have seen—feel free to google mycetoma or Madura foot if you care to see pics.

Overall it was a pretty grueling week. There were several other compelling, sad cases this week (that I’m not including here but may show up later) along with the huge daily dose of poverty and disease. In addition we worked like dogs to complete the first stage of our community health projects and choose our topics. I’m sure I’ll be writing lots more about this, but I’m going to focus on malaria in pregnant women, and Shalina is focusing on malnutrition in kids under five. They are both big issues here, and I really sincerely hope we can the community before we leave!